Publications

A. Dashti, G. Mashayekhi, M. Shekhar, D. Ben Hail, S. Salah, P. Schwander, A. des Georges, A. Singharoy, J. Frank, A. Ourmazd. Retrieving functional pathways of biomolecules from single-particle snapshots. Nature Communications, 2020, 11, no. 1 : 1-14.

• PubMed PMID: 32948759
• PubMed Central PMCID: PMC7501871
• ManifoldEM Matlab
• Binding Affinity Github Repo
• EMD-20486, EMD-22393, EMD-22395, EMD-22394, EMD-22396, EMD-22392, 6PV6, 7JMG, 7JMI, 7JMH, 7JMJ, 7JMF, EMPIAR-10315

T. C. Marcink, T. Wang, A. des Georges, M. Porotto, A. Moscona. Human parainfluenza virus fusion complex glycoproteins imaged in action on authentic viral surfaces. PLoS pathogens, 2020, 16, no. 9: e1008883.

• doi: 10.1371/journal.ppat.1008883
• PubMed PMID: 32956394
• PubMed Central PMCID: PMC7529294

T.C. Marcink, E. Yariv, K. Rybkina, V. Más, F. T. Bovier, A. des Georges, A. L. Greninger et al. Hijacking the Fusion Complex of Human Parainfluenza Virus as an Antiviral Strategy. Mbio, 2020, 11, no. 1.

• doi: 10.1128/mBio.03203-19
• PubMed PMID: 32047132
• PubMed Central PMCID: PMC7018645

X. Xu, R. Godoy-Ruiz, K. A. Adipietro, C. Peralta, D. Ben-Hail, K. M. Varney, M. E. Cook et al. Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di-heptamer macromolecular assembly. Proceedings of the National Academy of Sciences, 2020, 117, no. 2: 1049-1058.

• doi: 10.1073/pnas.1919490117
• PubMed PMID: 31896582
• PubMed Central PMCID: PMC6969506

A.H. Nguyen, A. R. B. Thomsen, T. J. Cahill, R. Huang, L. Huang, T. Marcink, O. B. Clarke, A. des Georges et al. Structure of an endosomal signaling GPCR–G protein–β-arrestin megacomplex. Nature structural & molecular biology, 2019, 26, no. 12: 1123-1131.

• doi: 10.1038/s41594-019-0330-y
• PubMed PMID: 31740855
• PubMed Central PMCID: PMC7108872