- Affiliate Faculty, Structural Biology Initiative
- Associate Professor of Molecular Pathobiology, NYU College of Dentistry
Since his first class on the subject, Des Georges has been fascinated by protein structures and allosteric control. He found electron microscopy to be a compelling tool to study their function and dynamics, and he joined the Linda Amos lab for his Ph.D to learn its techniques. He subsequently joined the Joachim Frank lab to learn the single-particle technique during his postdoctoral studies.
Still excited by its ability to visualize proteins directly, he continues to foray into the study of protein dynamics with cryo-electron microscopy, trying to learn as much as he can on the allosteric modulation of membrane proteins and on the role this plays in cell signaling. He enjoys exploring science with others, as a conversation in the pursuit of knowledge. He believes in fostering these conversations within his group to make science a fun and exciting pursuit.
The des Georges lab studies structural and functional study of the regulation of large macromolecular complexes using cryo-electron microscopy.